Major depressive disorder: Causes

The tendency to develop depression may be inherited: according to the National Institute of Mental Health[22] there is some evidence that depression may run in families. Most experts believe that both biological and psychological factors play a role.
Brain chemicals called neurotransmitters allow electrical signals to move from the axon of one nerve cell to the soma of another. A shortage of neurotransmitters impairs brain communication.
Brain chemicals called neurotransmitters allow electrical signals to move from the axon of one nerve cell to the soma of another. A shortage of neurotransmitters impairs brain communication.